Page 10 - Scientific Library
HSCI's researchers switch skin cells into pain-sensing neurons
In a recent publication, Dr Clifford
6 Tips for a successful ELISA
ELISA are immunoassays widely used in biomarker detection and validation. They have been used in research and clinical settings for more than 40 years, and they allow to quantify, in a simple way, thousands
Sample interference in ELISA tests
A previous post explained how samples obtained from patients treated with mAbs can show interference with WB & ELISA methods. More rarely, we can also find other interference effects
Hyaluronic acid - size matters!
Hyaluronic acid (HA), or hyaluronan, is an ubiquitous, very high molecular mass polysaccharide that has applications
Diluting samples for proteomics – biomarker profiling case studies (I)
To dilute or not to dilute biological samples? And if yes, how much? That's the question!
Following our post on whether samples should be pooled or not when performing studies for
Biomarker profiling: Diluting samples case studies (II)
Back to dilution of samples. After our post on whether samples should be diluted or not, let's discuss today about how much they should be diluted.
Case # 1 - ELISA or simplex
Get your ELISA results before lunch!
ELISAs are widely used in biomarker-related studies, especially when a high number of samples is involved, and only a few biomarkers need to be quantified. That said, incubations can be somehow cumbersome,
Focus on apolipoproteins
Apolipoproteins, with amphipathic properties, form lipoprotein particles with phospholipids and transport hydrophobic lipids through lymphatic
High resolution structure of the TRPA1 channel protein
One of the hottest news last month was the high resolution structure of the TRPA1 ion channel protein.
Thiostrepton: a novel lead compound against Dengue?
Dengue Virus (DenV) is transmitted by mosquito vectors. It infects 50-100 million people each year and is at the origin of Dengue Fever and the more lethal Dengue Hemorrhagic Fever (DHF) and Shock Syndrome
From osteoarthritis to bladder cancer... hyaluronic acid is not just cosmetics!
Hyaluronic Acid (HA) is important in many biological processes such as wound repair, tissue hydration and inflammation. HA is also a potential biomarker for diseases such as osteoarthritis, liver cirrhosis