Page 5 - Scientific Library
Specific cytokines & growth factors in... hematology!
Hematology is the study of blood, blood-forming organs and blood diseases. The formation of blood cells is referred to as hematopoiesis. All cellular components of the blood are derived from hematopoietic
Specific cytokines & growth factors in... apoptosis!
Apoptosis is the process of programmed cell death. Upon induction of apoptotic processes, cell undergo characteristic morphological changes (blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation,
5 new research tools to perform chromatin and epigenetic analysis
Nucleosomes are core particles involved in DNA packaging in eukaryotic cells. They affect gene expression levels by regulating access of DNA to transcription factors and DNA binding proteins. Nucleosome
Site-specific modified-histone substrates
Recombinant Histone proteins are popular research solutions in Drug discovery and Epigenetics studies. They can be used as in vitro positive controls in the analysis of post-translational Histone
microRNAs: Keys to open cell biology’s secret chamber
As cell biologist, when working in labs I have in the past witnessed several “X-files” in a flask of cells along my way: all cells of an established cell line are supposed to have the same genetic background
Cytokines and growth factors in Angiogenesis
Angiogenesis is the growth process of new blood vessels from pre-existing one's. It's a normal physiological process, observed during embryonic development. But it's also a pathological process, essentially
microRNAs: Finding the effector - miRNA detection
Following on from my previous post in which I started to introduce a series of techniques to investigate the impact of miRNA expression on cell fate,
microRNAs: Push and observe - miRNA overexpression
In this third post of the miRNA-related series, let's take a look at miRNA overexpression.
miRNA mimics
Short RNAs are very prone to enzymatic degradation. Novel chemical technologies now
microRNAs: Inhibiting the inhibitors - Antagomirs
Following on in our series on microRNAs (miRNA - Keys to open cell biology’s secret chamber)
microRNAs: Target detection
Leading on from my previous posts (see below) exploring microRNA detection, overexpression and inhibition, this time, let's spend a moment on target detection.
miTarget databases
Focus on the Hypoxia Regulation Mechanism
The cellular and physiological effects resulting from hypoxia-dependent networks have been clearly shown to impact a number of human pathological states, including ischemic disease, diabetes, pulmonary
How to probe motor-domains of kinesins?
In the past, molecular motor proteins like kinesins have been investigated with macromolecular approaches. Recent research on kinesins has been focused on resolving how kinesin is regulated by intramolecular