Page 8 - Scientific Library

Following on from my previous post  in which I started to introduce a series of techniques to investigate the impact of miRNA expression on cell fate, let's take a look at the first one: miRNA detection

In this third post of the miRNA-related series, let's take a look at miRNA overexpression.

miRNA mimics

Short RNAs are very prone to enzymatic degradation. Novel chemical technologies now allow RNA stabilization

The U.S. Food and Drug Administration (FDA) has approved Velcade (Bortezomib) for the retreatment of adult patients with Multiple Myeloma who had previously responded to Velcade therapy and relapsed

Following on in our series on microRNAs (miRNA - Keys to open cell biology’s secret chamber) , in this post, we'll be taking a look at Antagomirs (which are also called anti-miRs or blockmirs). These

Leading on from my previous posts (see below) exploring microRNA detection, overexpression and inhibition, this time, let's spend a moment on target detection.

miTarget databases

There are many online

Antibody pairs have been used for years to detect biomarkers in biological samples. They are a convenient and price-wise alternative to ready-to-use ELISAs, especially when they are used on a routine basis

The cellular and physiological effects resulting from hypoxia-dependent networks have been clearly shown to impact a number of human pathological states, including ischemic disease, diabetes, pulmonary

DNA topoisomerase I and DNA topoisomerase II (Topo I and Topo II) are nuclear enzymes which regulate the topological state of the DNA helix by transiently breaking and rejoining DNA strands. They also

Current cancer vaccine strategies strive to efficiently deliver in situ

Cytoskeleton modeling molecules are relevant when trying to improve one's understanding of cytoskeletal molecular modeling and associated mechanisms. Together with actin binding proteins, tubulin-based

With more than 100 types of cancers affecting any part of the body, cancer is one of the leading causes of death in the world. It has an enormous impact on well-being, both for those with the diagnosis