Page 8 - Scientific Library
How is Amylo-Glo a brighter, longer lasting and higher definition Amyloid plaque marker?
In a previous post I discussed 3 new unique research tools for analyzing Amyloid peptide in Alzheimer’s Disease (AD). Today, I'd like to come back to the unique properties of the Amylo-Glo® fluorescent
Bioactive small molecule sourcing - when quality meets expectations
Bioactive small molecules facilitate numerous types of Life Science research approaches (enzyme substrates, activators and inhibitors, cell signaling modulator, cell culture...). Accessing reasonably
3 monoclonals to discriminate free Ubiquitin from linear and polyubiquitin chains
Ubiquitin (Ub) is an 8 kDa  highly conserved polypeptide, commonly expressed in eukaryotic cells. Ub is added to lysine residues of the target proteins. This post-translational modification (known
Celastrol inhibits NF-kB pathway in Multiple Myeloma
Celastrol is a biologically active substance initially described in the traditional Chinese medicine. Celastrol (or (9ß,13α,14ß,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic
IP3-mediated STIM1 oligomerization requires intact mitochondrial Ca2+ uptake by Deak et al.
Deak AT et al. decipher the mechanisms by which mitochondria contribute to Ca2+ intracellular signaling. In their recent paper (1), they show that mitochondrial "Ca2+ buffering" close to the Endoplasmic