Scientific Library
Article
O-Glucuronide synthesis made easy
August 19, 2015
Glucuronide formation can be a major avenue of drug metabolism. O-Glucuronidation enhances the bile/plasma ratio of a metabolite relative to the parent drug. However, glucuronides are more polar and ionic
Article
Recombinant CYP Bactosomes: versatile formats for many ADME applications
February 22, 2018
Recombinant CYPs are commonly used in ADME-Tox studies as in vitro tools, mostly for reaction phenotyping, enzyme inhibition screening, clearance and metabolite ID.
"Research