Page 4 - Scientific Library
New Glycan Array - Sweet 17? Sweet 100!
Glycocalyx, literally meaning 'sugar coat', is an extracellular polymeric coating surrounding many prokaryotic and eukaryotic cells that consists of glycoproteins, glycolipids, proteoglycans and glycosaminoglycans.
Discovery of new biomarkers... 3 tips regarding controls
One of the recurrent questions that we get at the Biomarkers team at tebu-bio is on what controls should be included in a given experiment. Either if the experiment is done by researchers in their lab,
miRNAs: potent biomarkers in cancer research?
A recent paper by Kojima, M. et al. has found
How sample preparation can affect your biomarker studies (I)
In previous posts, we have discussed about whether samples should be pooled, how much (and if) they should be diluted, and how biologicals can affect the final results...and the biomarkers that you find.
Oxygen and miRNAs in Cosmetology and Dermatology
A recent review by Nadim et al. casts some light on a Cosmetology and Dermatology, where circulating biomarkers, though studied to a certain extent so far, are yet unknown for many skin models. (1)Â
Monoclonal antibodies validated for PTM studies
Knowing the Human genome better has allowed major advancements in Personalised Medicine. Nowadays, we can know (if we want) the likelihood to develop a given disease and/or how we will react to different
58 different human RTKs in one phosphorylation array
The Receptor Tyrosine Kinases (RTKs) are an important family of cell-surface receptors transmitting extracellular stimuli (ex. NGF, PDGF, FGF, EGF, Insulin...) into intracellular protein-tyrosine kinase
See how researchers get good quality publications with arrays
New findings in the TGF-beta pathway
Three papers on the role of the TGF-beta pathway in different cancers have recently been published.
It was already known that this pathway is involved in processes such as cell growth, cell differentiation,
A focus on the Wnt Pathway
The Wnt cell signalling pathway is a high-potential therapeutical target in cancer research. It's deeply linked to cellular fate through modulating cell proliferation, mobility, interaction, and polarity.
Find metastatic biomarkers in osteosarcoma!
Early in 2015, researchers of The University of Queensland Diamantina Institute (Australia) have shown a very sensible approach to the discovery of new biomarkers associated to transition from non-metastatic
Biomarkers of stemness
Stem Cells: a great tool for biomedical research! From the embryo at a very early stage of development, stem cells have two important capabilities: to multiply to infinity by simple division and to give