Page 5 - Scientific Library
How to optimise your recombinant protein purification and protein production
Undoubtedly, producing and purifying a protein is an art form.
Indeed, each recombinant protein (rec. protein) to be produced in vitro
New Reporter cell lines for Drug discovery and Immunotherapy checkpoint research
In the last few decades, in the field of Drug Discovery, Immunotherapy has gained more and more importance for the treatment of various diseases and in particular for certain types of
Breast Cancer - Popular validated primary antibodies for research and biomarker discovery
Use of validated antibodies is primordial for Breast Cancer research and related biomarker discovery. Here, we'll review the main biomarkers involved in this disease and introduce the
ELISA test to confirm elimination of Host Cell Proteins (HCP) from bioproductions
Expression systems - removing their contaminants
CHO, E. Coli and Pichia are useful expression systems for drug production. This can be for proteins, enzymes or antibody productions. Research and
Immunotherapy research: Easily build your own reporter cell line
As discussed previously in our recent Drug Discovery post, Immunotherapy is one of the central research fields for various disease treatments and also certain cancers. A major regulator
Tips and Tricks - Protein purification and production for LC-MS characterization
Mass spectrometry is a technology which is widely used in most scientific disciplines that require accurate and precise measurement of elemental and molecular components. Its use in the pharmaceutical
How to easily screen adenosine A2AR agonists and antagonists
Recently, BPS Bioscience have released a new Adenosine A2A Receptor (A2AR / ADORA2A) Functional Recombinant Cell Line for screening A2AR agonists and antagonists. An excellent means to
4 Tips to boost mRNA in vitro transcription and optimize mRNA delivery
Over the last years, mRNA-based experimental approaches have been successfully used in a broad range of research applications (genome editing, gene replacement, vaccine, immunotherapy, cellular reprogramming...)
Pluripotent Stem Cells and iPSC Research: Quality and Innovative Products
Since the discovery of reprogramming factors in 2006 and the boom of CRISPR gene editing strategies, induced pluripotent stem cells (iPSC) have emerged as new cellular models. The development