Page 5 - Scientific Library

In a recent paper published in PNAS, Wang et al. show that the inhibition of the deubiquitinase USP9x by the small molecule WP-1130 is able to induce degradation of the transcription factor E-twenty-six

Hypoxia in tumors is closely associated with tumor aggressiveness and resistance to radio- and chemotherapeutic treatment. Therefore, reliable markers for hypoxia represent both valuable diagnostic markers

To pool or not to pool biological samples? This question might pop up in the mind of anyone designing biomarker discovery approaches!

Much debate has been raised on biomarker discovery from clinical

Cancer research is increasingly focusing on the tumour microenvironment (TME). Several studies have shown that tumours depend on external signals for maintenance and expansion. It is therefore needed

Pneumococcus, or scientifically speaking, Streptococcus pneumoniae, is a pathogen responsible for a number of illnesses, including pneumonia, ear infections, sinus infections, meningitis and bacteremia.

The zebrafish (Danio rerio) is a common vertebrate model organism in scientific research for studying vertebrate development, gene function, and regenerative abilities. Interestingly, this convenient

We all react to external factors, even the most cold-blooded person. We might hide our emotions, but there they are.

The same happens in cancer. Cells (both the tumour cells and the normal ones) react

ISG15 ubiquitin-like modifier (ISG15) functions intracellularly as a Ubiquitin homologue and a cytokine. ISG15 induces production of IFN-gamma and augments NK/lymphokine-activated killer cell proliferation

As discussed in previous posts, use of new tools allows the finding of new disease-related biomarkers. Today, we want to put our spotlight on esophageal cancer.

A recent alliance between Quansys Biosciences

The word "cancer" groups a series of diseases of different origin and different prognosis, with differentiated molecular mechanisms causing their onset and progression. Hence, discovery of novel biomarkers

Neurotrophins are important biomarkers in Neurobiology, including stem cell development to neural lineages. BDNF and NGF are the ones being studied in most cases. However, it has been found that neurotrophins

Following our post on tumour microenvironment and glioblastoma, we will focus today on ameloblastomas.

Ameloblastomas are benign tumours that occur in the jawbone, and invade bone. This type of tumour