Scientific Library

Which roles do IDO and TDO play in Immunotherapy? Immune evasion is one of the identifying hallmarks of cancer and researchers are investigating the complex mechanisms that enable cancer

In a recent post, I concentrated on the role of HDACs in cancer: Histone Deacetylases (HDACs) and Cancer and mentioned that some HDACs are overexpressed and show very high activities in

Knowledge about which epitopes are recognized by a blocking antibody can help researchers to develop

Trpytophan (trp) is an important and essential amino acid that has a variety of functions within the cell. In addition to being incorporated

Interleukin-17 (IL-17) is a family of 6 closely related cytokines, designated IL-17A-F, that play a central role in mediating inflammation, autoimmunity,

Over the past months, we have released a number of posts introducing inhibitor screening assays intended to investigate immuno checkpoint

There is an increasing demand for new cholesterol-lowering therapies in addition to existing treatments (e.g. targeting statins). The pharmacological inhibition of PCSK9-mediated LDLR degradation

Extracellular adenosine 5'-triphosphate (ATP) is released by dying and damaged cells, and it acts on many immune

Over the last several years, the Immune System has appeared as a central, priority target to fight cancer and various other diseases. Currently,