Page 9 - Scientific Library
Article
Return of SIRT1 deacetylase - Why is SIRT1 so attractive in Drug discovery and Stem cell research?
May 06, 2014
SIRT1 is a NAD dependent class III Histone Deacetylase (HDAC). The tumor suppressor p53 is not the unique SIRT1 substrate. SIRT1 also deacetylates various key protein targets (PTEN, FOX, HIF-1
Article
Mutant or wild-type: 7 effective means to screen and profile Human EZH2 Methyltransferase
May 07, 2014
Histone-lysine N-methyltransferase EZH2 is a methyltransferase involved in transcriptional gene regulation. Together with with EED, RbAP48, SUZ12 and AEBP2, EZH2 forms a 5-member complex that adds 3 methyl