Scientific Library
Capping, bundling, sequestering... the role of Actin Binding Proteins
Actin binding proteins (ABPs) have a wide variety of functions in regulating the cellular function of actin. They control G-actin polymerization but also drive actin filaments severing and cross-linking
Genetically encoded fluorescent biosensors for live cell discovery
In drug discovery screening campaigns as well as in fundamental research activities, cellular parameters have to be measured and monitored in living cells regularly. Often fluorescent dyes are used to
cAMP signals visualized in live human pancreatic primary cells
In a recent publication, researchers from the University of Miami Miller School of Medicine (USA) describe that Serotonin released by human beta cell inhibits glucagon secretion by alpha cells. They demonstrated
Optogenetic tools: easily control cAMP production in cells with Light
Non-invasive manipulations of intracellular processes have recently appeared as an emerging research field. Experts in the development of biosensors for live cell discovery, Montana Molecular provide an
Reprogramming stem cells: a new innovative technology for the development of consistent and functional human cells
To overcome current cell model limitations, bit.bio have developed a new, innovative technology to reprogram human stem cells with precise control of transcription factor expression through iPSC engineering.
Consistent, scalable human iPSC-derived glutamatergic neurons and skeletal myocytes
As detailed in a separate post, bit.bio have developed a novel cellular reprogramming technology, opti-ox™1 (optimized inducible overexpression), that can generate functional cells with high consistency