Page 6 - Scientific Library
Pharma/biotech industry outsourcing trends in Biomarker studies
A recent article by E. Langer
How to easily obtain a highly purified untagged recombinant protein
Isolation of highly purified untagged proteins is crucial in today's R&D programs. Up to now, recombinant protein production approaches were often based on the use of "tags" to make protein purification
STAT3 signaling effects on IL-15 derived dendritic cells
The role of STAT3 signaling in the activity of dendritic cells (DC) has been recently revealed in a publication by Okada et al.
Which endotoxin testing assay in bioproduction?
Pharmaceutical, biotech and medical device industries apply restrictive quality systems in their bio-production processes. Among the numerous parameters controlled daily by scientists, I have selected
Angiogenin favours liver cancer (HCC) growth & expansion
A publication earlier this year by Bárcena et al. shows that angiogenin plays a crucial role in the onset and development of liver
SUMO-tag: boost your recombinant protein expression
SUMO-tag gene fusion acts as both a chaperonin and as an initiator of protein folding in both prokaryotic and eukaryotic systems. Addition of this tag enables protein experts to increase the expression
How sample preparation can affect your biomarker studies (II)
In a previous post, we looked at the importance of sample preparation
6 active compounds to rediscover rare bacterial metabolites
Microbial metabolites are a source of unequalled elements for in vitro assays. Sometimes neglected, these active molecules naturally provide a large spectrum of structural diversity for Drug
TUBEs: study M1 (linear) polyubiquitylated proteins
Traditional methods to detect and purify poly-ubiquitinated proteins require either anti-ubiquitin antibodies or Ubiquitin Binding Associated domains (UBAs). Most of the current methods display rather
Antibody purification troubleshooting tips
Antibody-based techniques are widely used in Life Science laboratories. Antibody purification is often required to raise purity yield of antibody production batches or to reach publication-grade data.
Biomarkers of stemness
Stem Cells: a great tool for biomedical research! From the embryo at a very early stage of development, stem cells have two important capabilities: to multiply to infinity by simple division and