Page 3 - Scientific Library
ORF expressing Lentiviral system
ORF expression in Mammalian cells is very useful for many applications: protein production with HEK293, over-expression of tagged protein for immuno-tracking or immuno-precipitation, development of a cell
Primary cells: ready-to-use, QC tested media
In a previous post, I introduced a complete panel of ready-to-use specialized media for smooth muscle primary cells culture. Produced by Cell Applications, a GMP certified
Gene knock-out in hard-to-transfect cells
Gene knock-out, which is gene editing leading to loss of function, just requires delivering into cells the 2 CRISPR system actors: the CAS9 endonuclease and the specific guide RNA to target
Five new fluorescent probes to easily image live cellular processes
Real time visualization of cellular events by Live Cell Imaging (LCI) has led to a better understanding of the global dynamic biological process. In a constantly evolving field, tebu-bio
New - you know CRISPR, now it's Prime Editing
This month, a new leap forward in gene editing has been published in Nature under the title 'Search-and-replace genome editing without double-strand breaks or donor DNA'. DOI: 10.1038/s41586-019-1711-4.
World's first 3',3'-Cyclic CAMP ELISA
The cGAS-cGAMP-STING cell signalling pathway plays a critical role in antiviral and antitumor immunity as well as mediating autoimmune responses. Dysregulation or aberrant activation of
How to monitor inflammatory cytokines in anti-COVID drug discovery
The close relation between Severe Acute Respiratory Syndrome (SARS), unpaired adaptive immune responses and overexpression of inflammatory cytokines has been described more than a decade
COVID-19: relevant cell culture models
One of the challenges in respiratory research in general, and for COVID-19 related projects in particular, is to have access to relevant in vitro cell culture models. Human lung
Three new pseudoviruses for SARS-CoV-2 studies
To better understand the mechanism of SARS-CoV-2 cell entry, BPS Bioscience have developed 3 new pseudotyped lentiviruses, allowing
Human and Viral proteases as targets for SARS-CoV-2 treatment?
Researchers have shown that proteases are actively used by SARS-CoV-2 for it's entry and replication into human cells. To support research on this topic, tebu-bio provides
Reprogramming stem cells: a new innovative technology for the development of consistent and functional human cells
To overcome current cell model limitations, bit.bio have developed a new, innovative technology to reprogram human stem
Siglecs as the new immunecheckpoint target
Due to their involvement as checkpoints in immune cell responses, Sialic-acid-binding ImmunoGlobulin-like Lectins (Siglecs) have gained more and