Page 14 - Scientific Library
Glycosylation studies in the inflammasome
In a previous post on tumour microenvironment (TME) and glycosylation, we indicated that new tools for studies on glycosylation of proteins were being developed. We are happy to announce
Immunotherapy Screening - GITR:GITRL pathway
In previous blogs, I invited you to read about the relevance of the B7-1
3 Reasons to use fresh TLR9 agonists
As part of the innate immune response, Toll-like receptor 9 recognizes unmethylated CpG nucleotide sequences, which are very common in viruses and prokaryotes and more rare in vetebrates. Scientists routinely
Immunotherapy Screening - CD40:CD40L pathway
In my previous blogs, I invited you to read about the relevance of the B7-1
Physioxia or Hypoxia: what it's all about
Cell culture under oxygen controlled conditions: an improvement towards more predictive results
Oxygen concentration in tissues is a key factor for cell and organ survival. In normal conditions,
Immunotherapy Screening - CD137:CD137L pathway
In previous blogs, I invited you to read about the relevance of the B7-1
Actin staining techniques in fixed and living cells
Actin can be stained in living and fixed cells to determine and follow the structure and function of the cytoskeleton. The actin cytoskeleton is a very dynamic and labile structure in the living cell,
Predicting CYP induction in stable cell lines
Assessing gene transcription as an endpoint for determining induction of drug metabolizing enzymes and transporters has become the “method of choice” in the FDA’s latest draft Guidance for Industry drug
Erythropoietin - active EPO for... hematologists!
EPO has a reputation with many non-scientists through bad press in the cycling/racing environment. From a researcher's point of view, Erythropoietin or EPO is a 34 KDa glycoprotein known as the