Page 2 - Scientific Library
Evaluating Clearance by Aldehyde Oxidase (AO): The Impact of Low Versus High AO Activity
An interesting poster has recently been published by XenoTech: "Selection of Human Liver S9 and Cytosol Fractions for Evaluating Clearance by Aldehyde Oxidase (AO): The Impact of Low Versus High AO Activity
Rat liver tritosomes in the endosome-lysosome pathway
Rat liver tritosomes are hepatic lysosomes that have been loaded with Tyloxapol (Triton WR 1339), a non-ionic surfactant. Tyloxapol is taken up by hepatocytes through endocytosis and is trafficked to lysosomal
ADME-Tox: liver fractions with High Aldehyde Oxidase and Xanthine Oxidase Activity
Sekisui XenoTech has just established a method for high Aldehyde Oxidase and Xanthine Oxidase activity in pooled Human liver test systems.
These new test systems (Pooled Human Liver
New CryostaX® Rodent Hepatocytes - largest pools available, easy-to-use pellet format
Sekisui XenoTech have announced the addition of Rodent Hepatocytes to their patented CryostaX® product line.
The CryostaX® in vitro drug discovery and preclinical drug
Human Liver Lysosomes for in vitro catabolism testing
In this post, I'd like to introduce the Human liver Lysosomes developed by Sekisui-Xenotech, which have opened up a new era in catabolism models. Read on to learn more, and also to download a case study
Achieve success with RNA-based CRISPR-CAS9 knock-out
RNA-based CRISPR-CAS9 gene editing is a vector-free approach that is required for therapeutic perspectives. However, from a practical point of view, what appears as a major challenge to engineer
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