Page 4 - Scientific Library

Autotaxin (ATX) is a secreted lysophospholipase D involved in the release of the lipid mediator LPA. Many research tools have been developed to study ATX-LPA signaling.  In this post, I invite you

Extracellular adenosine 5'-triphosphate (ATP) is released by dying and damaged cells, and it acts on many immune cells to promote

Today, I'd like to give you an overview about methods in actin research with validated R&D products and kits which will allow you to measure binding to actin and effects on the polymerisation dynamics

The JAK/STAT pathway is an important signalling process for numerous cytokines and growth factors.

Its activation is essential to many processes such as hematopoiesis,

Progesterone derived Allopregnanolone (ALLO) is an extensively studied neurosteroid that has been shown to be involved in neurodegenerative diseases, including Alzheimer's, Parkinson's disease, and multiple

The mitogen-activated protein kinase (MAPK) signaling pathway is activated by a number of extra and intracellular stimuli including cytokines, growth factors, and hormones as well as stressors such as

Sequence engineering and chemical modification of CAS9 mRNA

For transgenesis and

The Ras-Raf-MEK-ERK Pathway is an important cell signalling route with many implications for cancer biology and therapeutic development. Dis-regulation of some of this pathway's proteins expression and

Vector-free CRISPR-CAS9 gene editing to accelerate therapeutic applications

A few years ago, Ayal Hendel et al (doi:10.1038/nbt.3290) published results revealing that chemical alterations to sgRNA enhance

Over the last several years, the Immune System has appeared as a central, priority target to fight cancer and various other diseases. Currently, in cancer

How do you detect 300 specific glycan binding proteins in one experiment? Well, in this post we'll answer this question by introducing the new Glycan Array, developed by RayBiotech for your cell signalling