Page 29 - Content

The CRISPR-CAS9 system may well have opened Pandora's box, but it is also definitely the cornucopia of genome editing.

We can do what we want in the genome: settle a mutation, correct a mutation, insert

Early in 2015, researchers of The University of Queensland Diamantina Institute (Australia) have shown a very sensible approach to the discovery of new biomarkers associated to transition from non-metastatic

Knowledge about which epitopes are recognized by a blocking antibody can help researchers to develop improved antibodies

Transporters have become increasingly important in drug development due to the major role they play in absorption, distribution and excretion of endogenous

Antibody-based techniques are widely used in Life Science laboratories. Antibody purification is often required to raise purity yield of antibody production batches or to reach publication-grade

The treatment of diseases by inducing, enhancing, or surpressing an immune response is referred to as Immunotherapy.

Traditional methods to detect and purify poly-ubiquitinated proteins require either anti-ubiquitin antibodies or Ubiquitin Binding Associated domains (UBAs). Most of the current methods display rather

Deubiquitylating enzymes (DUBs) are promising therapeutical targets, especially in oncology (see my previous post dedicated to this topic). Today, I'd like to introduce you to new innovative

The Wnt cell signalling pathway is a high-potential therapeutical target in cancer research. It's deeply linked to cellular fate through modulating cell proliferation, mobility, interaction, and polarity.

Three papers on the role of the TGF-beta pathway in different cancers have recently been published.

It was already known that this pathway is involved in processes such as cell growth, cell differentiation,