Mouse anti-CD22/B-cells, clone MEM-01 (Monoclonal) - 0.1 mg

Datasheet
CD22, also known as Siglec-2 (sialic acid-binding immunoglobulin-like lectin-2) is a transmembrane glycoprotein binding alpha2,6-linked sialic acid-bearing ligands. Intracellular domain of CD22 recruits protein tyrosine phosphatase SHP-1 through the immunoreceptor tyrosine-based inhibitory motifs (ITIMs), thus setting a treshold for B cell receptor-mediated activation. CD22 also regulates B-cell response by involvement in controlling the CD19/CD21-Src-family protein tyrosine kinase amplification pathway and CD40 signaling. CD22 exhibits hallmarks of clathrin-mediated endocytic pathway.

Supplier Catalog Number

 MON1067

Shipping conditions

 Cool pack

Storage Temperature

 +4°C

Supplier name

 Sanbio Monosan
From
£366.00
Total £366.00

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Additional information

Host: Mouse
Clonality: Monoclonal