MC-Val-Cit-PAB-SN38 - 5 MG

MC-Val-Cit-PAB-SN38 is a cleavable ADC linker featuring a maleimide, a Val-Cit dipeptide, a PAB group and an SN38 warhead. Maleimide is a covalent ligand used for linking thiols such as those in cysteines residues in proteins, while the Val-Cit-PAB motif is an enzyme-cleavable linker. This linker efficiently releases the toxin, SN38, to target cells to cause cellular apoptosis.

Supplier Catalog Number

 BP-40210

Shipping conditions

 Room temperature

Storage Temperature

 -20°C

Supplier name

 BroadPharm

CAS Number

 1801838-28-7
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Additional information

CAS Number: 1801838-28-7
Formula: C51H58N8O13
Molecular Weight: 991.07671 Da