Scientific Library
Breast Cancer - Popular validated primary antibodies for research and biomarker discovery
Use of validated antibodies is primordial for Breast Cancer research and related biomarker discovery. Here, we'll review the main biomarkers involved in this disease and introduce the most popular validated
Cell signalling: How to easily detect mono- and poly-Ub target proteins
How to make Post Translational Modification characterization easier
Signal-Seeker assays (Cytoskeleton Inc.) provide researchers with the most comprehensive reagents enabling highly sensitive and specific detection of the key Post Translational Modifications (PTMs)
Cell signalling studies: Tips for selecting the best Small G Protein activation assay
Small GTP-binding proteins such as Rho and Ras GTPase family members are involved in regulating cell signalling pathways and impact a wide range of cellular processes, functions, and morphology. In this
Therapeutic Target - Ubiquitin-Proteasome system: What about tubulin?
The ubiquitin-proteasome system (UPS) is a well-characterized protein degradation system in cells whose dysfunction is implicated in many diseases, including neurodegeneration and cancer1,2. Major UPS
DDI studies: New TransiPort cells for OATP1A2 and OATP2B1 transporters
Membrane transporters can have clinically relevant effects on the pharmacokinetics and pharmacodynamics of a drug in various organs and tissues by controlling its absorption, distribution and elimination.
Powerful and reliable solutions to decipher Actin Dynamics
As is well known, the actin cytoskeleton is a highly dynamic structure, involved in a large number of cellular processes, including muscle contraction, lamellopodial extrusion, cell locomotion, cytokinesis,
Anti-Tag antibodies you can rely on: a focus on GFP and RFP
My colleague Ana introduced in a previous post (3 years ago already!) a selection of the most popular anti-tag antibodies among the research community. I must say that they remain extremely popular, showing
Fully licensed SLC cell lines for FDA and EMA recommended transporters
In a previous post, we introduced our Ready-to-use cellular models for SLC assays by GenoMembrane.
These cell lines transiently express the current FDA and EMA recommended SLC drug transporters (eg.
Immunoassay development: reliable sources of quality reagents
We understand how crucial it is to have access to sustainable, quality sources of reagents when developing and/or producing the same immunoassays over long periods of times. Over the years, we've established