Scientific Library

Lipodystrophies are disorders characterized by complete or selective loss of adipose tissue from various regions of the body. They might lead to severe metabolic disorders. The development of reliable

The World Health Organization (WHO) estimated in 2008 that 1.4 billion adults worldwide were overweight and of these 500 million were obese with risks for developing type 2 diabetes, hypertension and cardio-vascular

Mechanisms leading to cellulite formation is complex. It involves lipid regulatory pathways and proinflammatory cross-talk that represent promising molecular targets in cosmetology. This post introduces

Microtubules are key components of the cytoskeletal structure of eukaryotic cells. Composed of alpha- and beta- tubulin sub-units, microtubules are dynamic entities

Statins are HMG-CoA reductase inhibitors, well-known  medications for treating Hypercholesterolemia. Simvastatin is a member of this "Statin family" and controls

Human Peripheral Blood Mononuclear Cells (hPBMCs) are essential for designing cellular models to be used in cell therapy and drug discovery research programs [1-7, 12]. Being able to access reliable and

In the field of Drug Development, 3D cell culture models such as spheroids or organoids currently appear as one of the best solutions to obtain accurate and physiological in vitro data, closest to what

Recent articles have highlighted the role the STING cell signalling pathway may be playing in drug development, whether via its inhibition to control innate immunity and inflammation (Nature Biotechnology,

Oxidative stress can lead to diverse pathophysiological changes in the body. Neurodegenerative diseases such as Parkinson and Alzheimer are linked to oxidative

Our body is made up of trillions of cells grouped together to form tissues and organs. The genes present in the nucleus of every cell tell it when to grow, work, divide and die.

Normally, our cells follow

In medicine, biotech and pharmacology, drug discovery is the entire process to discover new candidate medications.

The process is long and complex, the budget needed is expansive and the skills required