Ppc-1 is a novel small molecule derived from cellular slime mould. In this post, I'd like to introduce the characteristics of this compound for your in vitro mitochondrial research.

In the field of Drug Development, 3D cell culture models such as spheroids or organoids currently appear as one of the best solutions to obtain accurate and physiological in vitro

Due to its involvement in many cellular processes such as normal ageing, tumor suppression, chronic diseases and many more, cellular senescence has gained increasing attention since its first description

With their polycationic properties, polyamine organic compounds are involved in various biological functions (DNA-RNA interaction, gene expression...), and can also be considered as cancer marker.

Involved in many physiological processes (apoptosis, aging, cell signalling..) and numerous diseases (cardiovascular disorders, to cancer and neuro-degenerative diseases…), Mitochondria have become more

Real time visualization of cellular events by Live Cell Imaging (LCI) has led to a better understanding of the global dynamic biological process. In a constantly evolving field, tebu-bio

All human and living beings have mitochondria. These are tiny cellular organisms present in nearly every cell of an individual. They are located more precisely inside the cells, in their nucleus. The main

Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

In their latest publication in Nature, Dr. Moiseeva et.al., studied cellular senescence in skeletal

Mitochondrial Dynamics and Mitochondria-Lysosome Contacts in Neurogenetic Diseases

In an article published in frontiers in Neuroscience, with the aim to study cellular phenotypes

Understanding cellular senescence and oxygen consumption rate

A recent paper published in Science reported a 50% reduction in mortality and improved immune response in old mice infected

Relationship between antitumor effects and active oxygen

ROS (Reactive oxygen species) are highly reactive oxygen species mainly generated during the ATP synthesis process in mitochondria.