Scientific Library
SiR fluorogenic probes: multicolour live-cell Imaging of Actin, Tubulin, DNA, and Lysosomes
Fluorescence microscopy: how to improve your Live Cell Imaging
For more than 2 years now, the Silicon Rhodamine-like (SiR) technology has allowed the live cell imaging field with fluorescence microscopy to evolve significantly.
Fluorescent
Live Cell Imaging - Watch SiR-Tubulin stained Human Osteosarcoma cells in action
As you may already know, Spirochrome have developed a broad range of Live Cell Imaging probes for the staining of DNA, Lysosome, F-Actin
Gold standard one component TMB
Tetramethylbenzidine (TMB) is a classic substrate for peroxidase activity that is used for microwell plate analysis such as an ELISA test. A quantitative color change from yellow to
STING: key player in drug development?
Recent articles have highlighted the role the STING cell signalling pathway may be playing in drug development, whether via its inhibition to control innate immunity and inflammation (Nature
3 colour Live Cell Imaging - Actin, Tubulin and DNA
Following on from the popular SiR-Probes, earlier this year Spirochrome introduced new SPY probes, as presented in
New Flipper-TR probes - easily measure membrane tension in cells
Despite its importance in the regulation of many cellular processes, membrane tension is still complicated to measure. And despite valuable insights, the techniques currently available remain complex and
New cutting-edge SPY labelling probes
With the great success of the SIR-probes for efficient labeling of the cell Cytoskeleton, DNA and Lysosome, Spirochrome have just
Immunotherapy for breast cancer: Types and effectiveness
Our body is made up of trillions of cells grouped together to form tissues and organs. The genes present in the nucleus of every cell tell it when to grow, work, divide and die.
Normally, our cells
CRO & Drug Discovery
In medicine, biotech and pharmacology, drug discovery is the entire process to discover new candidate medications.
The process is long and complex, the budget needed is expansive and the skills
Revolutionising Live Cell Imaging: Leveraging Novel Targeting Tools to Unlock New Frontiers in Cellular Research
The development of new probes marks significant progress in live-cell imaging. Peroxi_SPY555 and Peroxi_SPY650 are the first small-molecule probes designed specifically
Unveiling the Next Generation of Actin Imaging
Advancing Live-Cell Actin Imaging with Spirochrome New Products
Actin cytoskeleton imaging is a cornerstone of cellular biology, playing a pivotal role in understanding cell