Scientific Library
3 colour Live Cell Imaging - Actin, Tubulin and DNA
Following on from the popular SiR-Probes, earlier this year Spirochrome introduced new SPY probes, as presented in
New Flipper-TR probes - easily measure membrane tension in cells
Despite its importance in the regulation of many cellular processes, membrane tension is still complicated to measure. And despite valuable insights, the techniques currently available remain complex and
New cutting-edge SPY labelling probes
With the great success of the SIR-probes for efficient labeling of the cell Cytoskeleton, DNA and Lysosome, Spirochrome have just
Revolutionising Live Cell Imaging: Leveraging Novel Targeting Tools to Unlock New Frontiers in Cellular Research
The development of new probes marks significant progress in live-cell imaging. Peroxi_SPY555 and Peroxi_SPY650 are the first small-molecule probes designed specifically
Production of eGFP mRNA Labeled with Fluorophore for Tracking of Delivery and Expression
Our Contract Research Services (CRS) team developed eGFP mRNA labeled with a fluorophore to monitor its delivery and expression efficiency in cells.
RNA Production Platform and the Associated Solutions Facilitate the Development of RNA-Based Vaccines
RNA vaccines have shown their full potential in the Covid-19 pandemic. The application of these technologies for the treatment of cancers represents a significant promise, but clinical effectiveness remains
Standardized 3D Spheroid Systems Facilitate Drug Screening and Biomarker Identification with High Relevance for Cancer Drug Discovery
Our customer needed to investigate whether modulating key culture parameters could improve the predictivity of their colorectal cancer cell-based methodology used to select
Multiplex Antibody Array for Protein Profiling and Biostatistical Analysis to Assess the Effect of Oxaliplatin on Mouse Fibrosarcoma Cell Line
Oxaliplatin (OXA) is a chemotherapeutic drug which causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin is known as immunogenic cell death
Development of Cost Effective and Robust 3D Colorectal Cancer Models for Physiological Drug Response Analysis
Our customer needed to obtain in vivo like responses to drug treatment, through monitoring parameters such as gene expression, biomarker analysis,
Unveiling the Next Generation of Actin Imaging
Advancing Live-Cell Actin Imaging with Spirochrome New Products
Actin cytoskeleton imaging is a cornerstone of cellular biology, playing a pivotal role in understanding cell
Lipid Nanoparticles (LNP): The New Cargo for Drug Delivery
Explore how to optimize Lipid Nanoparticules (LNP) for mRNA delivery for druf development. This study highlights key formulation parameters: buffer
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Flexible Protein Production Services for Custom Expression & Purification
Tebubio’s Protein Production Platform