DNA methylation and histone post-translational modifications are key epigenetic factors.

They regulate

Nucleosomes are core particles involved in DNA packaging in eukaryotic cells. They affect gene expression levels  by regulating access of DNA to transcription factors and DNA binding proteins. Nucleosome

In the summer of 2013, my colleague Frederic Dubor, who is in charge of our services lab, mentioned to me that he had just been asked by 3 clients within a very short time-frame, whether our laboratory

Recombinant Histone proteins are popular research solutions in Drug discovery and Epigenetics studies. They can be used as in vitro positive controls in the analysis of post-translational Histone

Nucleosomes are basis units of DNA packaging in eukaryotic cells. A core particle (mono-nucleosome) consists of a segment of DNA called core DNA (147

Nucleosomes are basis units of DNA packaging in eukaryotic cells. A core particle (mono-nucleosome) consists of a segment of DNA called core DNA (147 bp in length)

Cell culture models using 2D substrates have provided important conceptual advances in understanding the biology of cells. However, cells grown on flat 2D surfaces can differ substantially from physiological

Chromatin profiling assays enable the mapping of protein-DNA interactions that influence chromatin modeling and gene expression.
Over the years, Chromatin ImmunoPrecipitation (ChIP) assays became

Developed by Epicypher and available in Europe through tebu-bio, CUTANA CUT&RUN and its sister technology CUT&TAG are quickly becoming the preferred approaches for Chromatin Mapping

Small molecules – overcome the barriers to clinical development

The potential of nanomedicine to provide therapeutic benefits over conventional drug formulations has been proven with a number of

Peptide advances in biomedicine

Peptides, which are short chains of amino acids, have gained significant attention in biomedicine due to their diverse applications. Their unique properties, such