Scientific Library
Obesity, Diabetes, Metabolic syndrome new research tools
Insulin and Glucagon are involved in glucose homeostasis in addition to other factors secreted by the adipose tissue (adipokines). Insulin and Glucagon are produced by the endocrine pancreas. While
Primary cell sourcing: Cryopreserved Human Adult Sebocytes
Sebocytes are emerging cellular models to study skin biology but also to design new compounds to regulate acne, seborrhoea and other sebaceous gland-related diseases. Easy access to cryopreserved and
Human Primary Sebocyte assay for compound testing on lipid metabolism
Sebocytes belong to the epidermal ecosystem together with hair follicules or in sebaceous glands. Sebocytes play a key role in skin health by producing sebum. These cells are now at the center of researchers'
Measure antioxidative capacities of your samples
Free radicals and Reactive Oxygen Species (ROS) are highly reactive molecules generated by normal cellular processes, environmental stress, and UV irradiation. ROS react with numerous cellular components
Easy and sensitive methods to measure antioxidative potential
Free radicals and reactive oxygen species (ROS) are highly reactive molecules that are generated by normal cellular processes, environmental stress, and UV irradiation. ROS react with cellular components,
PBMCs & drug development
Use of human samples including peripheral blood mononuclear cells (PBMCs)Â in drug discovery is critical for increasing the chances of success for a small molecule screen hit. A review based on recent
New in vitro cellular model for human Lipodystrophy
Lipodystrophies are disorders characterized by complete or selective loss of adipose tissue from various regions of the body. They might lead to severe metabolic disorders. The development of reliable
Anti cellulite compound evaluation with in vitro adipocyte-assays
Mechanisms leading to cellulite formation is complex. It involves lipid regulatory pathways and proinflammatory cross-talk that represent promising molecular targets in cosmetology. This post introduces
10 most popular antibodies in neuroscience research
Analysis of neuronal cell fates and biological activities sometimes relies on the effective staining of a protein of interest (a.k.a. marker) with a specific primary antibody validated for immuno-assays.
Human Islets for Research - Which factors affect their quality?
The islets of Langerhans are the regions of the pancreas that contain its endocrine (i.e., hormone-producing) cells. Discovered in 1869 by German pathological anatomist Paul Langerhans, the islets of Langerhans
Cell-based assays with hPBMCs for cell therapy and drug discovery
Human Peripheral Blood Mononuclear Cells (hPBMCs) are essential for designing cellular models to be used in cell therapy and drug discovery research programs [1-7, 12]. Being able to access reliable and
