Scientific Library

The U.S. Food and Drug Administration (FDA) has approved Velcade (Bortezomib) for the retreatment of adult patients with Multiple Myeloma who had previously responded to Velcade therapy and relapsed

The involvement of Prostaglandin E2 (PGE2) in cancer development has already been described (see the post "Tumour microenvironment – the dark side of PGE2). Recently, Kurtova et al. confirmed this

The World Health Organization (WHO) estimated in 2008 that 1.4 billion adults worldwide were overweight and of these 500 million were obese with risks for developing type 2 diabetes, hypertension and cardio-vascular

Microtubules are key components of the cytoskeletal structure of eukaryotic cells. Composed of alpha- and beta- tubulin sub-units, microtubules are dynamic entities

Statins are HMG-CoA reductase inhibitors, well-known  medications for treating Hypercholesterolemia. Simvastatin is a member of this "Statin family" and controls

Single-cell isolation allows genomic and transcriptomic analysis of one individual cell. It is also required to build a monoclonal cell line from rare cell isolation, that could be for example CRISPR-CAS9

The main challenge in RNA-sequencing workflow is certainly library preparation. When it's question of single-cell isolation and so 10-100 picogram of total RNA, the challenge may become mission impossible...

Recent articles have highlighted the role the STING cell signalling pathway may be playing in drug development, whether via its inhibition to control innate immunity and inflammation (Nature Biotechnology,

Our body is made up of trillions of cells grouped together to form tissues and organs. The genes present in the nucleus of every cell tell it when to grow, work, divide and die.

Normally, our cells follow

In medicine, biotech and pharmacology, drug discovery is the entire process to discover new candidate medications.

The process is long and complex, the budget needed is expansive and the skills required

According to the WHO (World Health Organization), early diagnosis of diseases is one of the key factors in the world to save lives and reduce the cost of treatment. Faced with these recommendations, in