Scientific Library
Establish if a treatment modulates immune response, even in a conflicting background
In a recently published study, researchers sought to elucidate if 2 treatments modulated immune response or not, despite the available evidence being conflicting. The method that made the difference and
How a multiplex ELISA helps development of rapid diagnostic tests
One of the challenges in R&D is to find robust technologies to develop diagnostic tests. Notably, it could be within a context of asymptomatic infections for which reliable detection of positive specimens
Study 10 cytokines and more for the price and simplicity of a single ELISA
I just want to briefly outline in this post the power of antibody microarray when it comes to time and cost saving as well as versatility. Whether you want to do multiple profiling or quantitative studies,
MitoTools: Mitochondrial research has never been so easy
Involved in many physiological processes (apoptosis, aging, cell signalling..) and numerous diseases (cardiovascular disorders, to cancer and neuro-degenerative diseases…), Mitochondria have become more
How to monitor inflammatory cytokines in anti-COVID drug discovery
The close relation between Severe Acute Respiratory Syndrome (SARS), unpaired adaptive immune responses and overexpression of inflammatory cytokines has been described more than a decade ago (1, 2).
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What mitochondria related diseases?
All human and living beings have mitochondria. These are tiny cellular organisms present in nearly every cell of an individual. They are located more precisely inside the cells, in their nucleus. The main
Senescent cells prevent muscle regeneration
Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration
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In their latest publication in Nature, Dr. Moiseeva et.al., studied cellular senescence in skeletal muscle, carrying
Mitochondria-Lysosome Contacts in Neurogenetic Diseases
Mitochondrial Dynamics and Mitochondria-Lysosome Contacts in Neurogenetic Diseases
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In an article published in frontiers in Neuroscience, with the aim to study cellular phenotypes in fibroblasts from
Why replace fluorescent markers with lanthanide nanoparticles to improve detection?
According to the WHO (World Health Organization), early diagnosis of diseases is one of the key factors in the world to save lives and reduce the cost of treatment. Faced with these recommendations, in
Understanding cellular senescence and oxygen consumption rate
Understanding cellular senescence and oxygen consumption rate
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A recent paper published in Science reported a 50% reduction in mortality and improved immune response in old mice infected with SARS-CoV-2
Relationship between antitumor effects and active oxygen
Relationship between antitumor effects and active oxygen
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ROS (Reactive oxygen species) are highly reactive oxygen species mainly generated during the ATP synthesis process in mitochondria. While it is
Alzheimer’s Amyloid-β Accelerates Cell Senescence and Suppresses SIRT1 in Human Neural Stem Cells
In this blog, discover three assay kits developed by our partner Dojindo to accurately quantify and detect SA-β-Gal activity, and to explore a broad range of cellular processes linked to senescence.