Scientific Library

Kv1.3 channels are expressed in T-cell lymphocytes and over-expressed in autoimmune diseases. They can be see as a therapeutic taget for T cell mediated autoimmune diseases.

ShK toxin (Stichodactyla helianthus

The neuropeptides, Oxytocin and Vasopressin, were isolated and synthesized by Vincent du Vigneaud at Cornell Medical College in 1953, work for which he received the Nobel Prize in Chemistry in 1955.

Acid-Sensing Ion Channels (ASICs) are neuronal voltage-insensitive cationic channels which are activated by extracellular protons. They belong to the ENaC/Deg superfamily of ion channels. Up to now 6

Ion channels are proteins with pore-forming abilities. Their selective capabilities to let ions cross the cell membrane involves them in crucial cellular functions (controlling membrance potential, the

Ions channels are pore-forming membrane proteins that control ion transit across the cell membrane to various stimuli. It was shown that deregulation or dysfunction of channels are clearly linked to many

Reactive Oxygen Species (ROS) are reactive molecules and free radicals derived from molecular oxygen involved in cellular homeostasis. An excess of ROS production (e.g. exposure to environmental stress

Progesterone derived Allopregnanolone (ALLO) is an extensively studied neurosteroid that has been shown to be involved in neurodegenerative diseases, including Alzheimer's, Parkinson's disease, and multiple

One of the biggest challenges as a researcher in life sciences, is to obtain proof of concept the more predictive as possible. To help you to reach your objectives, many innovative tools are being developed

By mimicking in-vivo environments, 3D cell culture models appear nowadays as the best in-vitro study model to work in an in-vivo like study model and to obtain more physiologically relevant data and proof

As mentioned in a previous post the DAX Biochips from AIM Biotech are an innovative and versatile microfluidic platform, allowing researchers to more easily develop 3D cell culture models, to work as close

When scientists at ArborAssays invented the Direct Cyclic Nucleotide EIA immunoassay more than 20 years ago, they knew the kits would be popular. The direct nature of the format for the assays allows cAMP

A new Hemoglobin (Hgb) High Sensitivity kit has just been released to allow for the detection of Hgb in low amount of samples. Researchers working on inflammation, kidney injury or oxidative stress may