Page 4 - Scientific Library
Useful tip for better zebrafish whole-mount IHC staining
The zebrafish (Danio rerio) is a common vertebrate model organism in scientific research for studying vertebrate development, gene function, and regenerative abilities. Interestingly, this convenient
Antibody arrays: a matter of species
Research is never easy. That's why we either like doing it or supporting it.
That said, it's easier for some researchers than others. If you are working on human, mouse or even rat models, you have quite
6 Tips for a successful ELISA
ELISA are immunoassays widely used in biomarker detection and validation. They have been used in research and clinical settings for more than 40 years, and they allow to quantify, in a simple way, thousands
Glycosylation studies in the inflammasome
In a previous post on tumour microenvironment (TME) and glycosylation, we indicated that new tools for studies on glycosylation of proteins were being developed. We are happy to announce that they are
Novel biomarkers in gastric cancer
The word "cancer" groups a series of diseases of different origin and different prognosis, with differentiated molecular mechanisms causing their onset and progression. Hence, discovery of novel biomarkers
Direct access to Biomarker Profiling identification tools
Profiling tools have an increasing interest for identifying new biomarkers. Different tools are available, from classical gene profiling on DNA chips, RT-qPCR arrays, Protein arrays for secretome or
Diluting samples for proteomics – biomarker profiling case studies (I)
To dilute or not to dilute biological samples? And if yes, how much? That's the question!
Following our post on whether samples should be pooled or not when performing studies for Biomarker discovery,
Biomarker profiling: Diluting samples case studies (II)
Back to dilution of samples. After our post on whether samples should be diluted or not, let's discuss today about how much they should be diluted.
Case # 1 - ELISA or simplex assays
Most ELISA manufacturers
Discovery of functional serum biomarkers
Lung cancer is one of the most common malignancies, and the leading cause of cancer-related fatality. Current diagnostic practices for common cancers rely heavily on imaging technologies. These
New biomarkers in periodontal disease
Periodontitis, also generally called gum disease or periodontal disease, begins with bacterial growth in the mouth and may end, if not properly treated, with tooth loss due to destruction of the tissue
mTOR revisited
The PI3K/Akt/mTOR pathway is an intracellular signaling pathway important in regulating the cell cycle. It is directly related to cellular quiescence, proliferation, cancer, and