Page 4 - Scientific Library

Following our series of posts on the role of exosomes in cancer (TME, signaling), let's have a look at Neurobiology today. Because exosomes are everywhere (even in beer!).

To dilute or not to dilute biological samples? And if yes, how much? That's the question!

Following our post on whether samples should be pooled or not when performing studies for Biomarker discovery,

Back to dilution of samples. After our post on whether samples should be diluted or not, let's discuss today about how much they should be diluted.

Case # 1 - ELISA or simplex assays

Most ELISA manufacturers

Lung cancer is one of the most common malignancies, and the leading cause of cancer-related fatality. Current diagnostic practices for common cancers rely heavily on imaging technologies. These

A wide range of in vitro models are used in preclinical drug testing for the investigation of ADME-Tox (Absorption, Distribution, Metabolism, Excretion and oxicity) properties of New Chemical Entities

Periodontitis, also generally called gum disease or periodontal disease, begins with bacterial growth in the mouth and may end, if not properly treated, with tooth loss due to destruction of the tissue

The PI3K/Akt/mTOR pathway is an intracellular signaling pathway important in regulating the cell cycle. It is directly related to cellular quiescence, proliferation, cancer, and

Glycocalyx, literally meaning 'sugar coat', is an extracellular polymeric coating surrounding many prokaryotic and eukaryotic cells that consists of glycoproteins, glycolipids, proteoglycans and glycosaminoglycans.

Chronic Mucosal Inflammation is the hallmark of common airway diseases (ex.  Allergic Rhinitis and asthma). Lipoxin B₄(LXB₄) is an endogenous mucosal protective mediator decreasing such diseases.

The determination of serum blood urea nitrogen (BUN) is currently the most widely used screening test for the evaluation of kidney function. The test is frequently run along with the serum creatinine test,

PGE₂ is a potent lipid mediator involved in maintaining homeostasis but also in the promotion of acute inflammation or immune

Rat liver tritosomes are hepatic lysosomes that have been loaded with Tyloxapol (Triton WR 1339), a non-ionic surfactant. Tyloxapol is taken up by hepatocytes through endocytosis and is trafficked to lysosomal