Luciferase is the general term given to a class of oxidative enzymes that catalyze reactions that give off light, a process known as bio-luminescence (Fig. 1). In biology,
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Article
Screen for inhibitors of PD-1 signalling with a complete cellular assay system
October 28, 2016
Immunotherapy represents a field in Drug Discovery which is quickly developing and leading to significant progress in treatments of a number of diseases, especially cancer. The approach is based on inducing,
Application Note
New - Continued use immunotherapy cell line expressing recombinant PD-1
February 03, 2017
PD-1/NFAT-Luciferase reporter jurkat cell line used to monitor the T cell response inhibition via PD-1 interacting with PD-L1/PD-L2
PD-1 / NFAT Reporter - Jurkat Cell Line
The PD-1 reporter cell line is
Article
New Reporter cell lines for Drug discovery and Immunotherapy checkpoint research
October 02, 2017
In the last few decades, in the field of Drug Discovery, Immunotherapy has gained more and more importance for the treatment of various diseases and in particular for certain types of cancer. Based on
Article
How can you improve your reporter gene assays?
October 20, 2017
Gene reporter assays are widely used in research and Drug Discovery. The development of such cell lines is often time-consuming and costly, sometimes upwards of 5-20k € per cell line. And once these cell
Article
Immunotherapy research: Easily build your own reporter cell line
October 23, 2017
As discussed previously in our recent Drug Discovery post, Immunotherapy is one of the central research fields for various disease treatments and also certain cancers. A major regulator of immune homoeostasis
Article
How to easily screen adenosine A2AR agonists and antagonists
February 20, 2018
Recently, BPS Bioscience have released a new Adenosine A2A Receptor (A2AR / ADORA2A) Functional Recombinant Cell Line for screening A2AR agonists and antagonists. An excellent means to efficiently evaluate