Page 2 - Scientific Library
How to select Hyaluronic Acid (HA) quantitative tests?
Hyaluronic acid (also called HA or Hyaluronan) is a glycosaminoglycan with unique characteristics. HA possesses elevated viscosity, enabling tissues (eye, skin, joint and synovial fluid...) to resist
Immunogenicity in biotherapeutics and biosimilars
Following on from my previous post on biosimilars and biotherapeutics (or biologics), let's now take a look at some of the specific criteria for this kind of compound, which are not normally required
Proteasome inhibitor approved by FDA for Myeloma retreatment
The U.S. Food and Drug Administration (FDA) has approved Velcade (Bortezomib) for the retreatment of adult patients with Multiple Myeloma who had previously responded to Velcade therapy and relapsed
Hyaluronic acid - size matters!
Hyaluronic acid (HA), or hyaluronan, is an ubiquitous, very high molecular mass polysaccharide that has applications in a variety
PGE2 role in carcinoma chemoresistance via CSC repopulation
The involvement of Prostaglandin E2 (PGE2) in cancer development has already been described (see the post "Tumour microenvironment – the dark side of PGE2). Recently, Kurtova et al. confirmed this
20S Proteasome inhibitors and Leptin against obesity
The World Health Organization (WHO) estimated in 2008 that 1.4 billion adults worldwide were overweight and of these 500 million were obese with risks for developing type 2 diabetes, hypertension and cardio-vascular
From osteoarthritis to bladder cancer... hyaluronic acid is not just cosmetics!
Hyaluronic Acid (HA) is important in many biological processes such as wound repair, tissue hydration and inflammation. HA is also a potential biomarker for diseases such as osteoarthritis, liver cirrhosis