Page 5 - Scientific Library

In this third post of the miRNA-related series, let's take a look at miRNA overexpression.

miRNA mimics

Short RNAs are very prone to enzymatic degradation. Novel chemical technologies now allow RNA stabilization

Cancer research is increasingly focusing on the tumour microenvironment (TME). Several studies have shown that tumours depend on external signals for maintenance and expansion. It is therefore needed

Following on in our series on microRNAs (miRNA - Keys to open cell biology’s secret chamber) , in this post, we'll be taking a look at Antagomirs (which are also called anti-miRs or blockmirs). These

Leading on from my previous posts (see below) exploring microRNA detection, overexpression and inhibition, this time, let's spend a moment on target detection.

miTarget databases

There are many online

The cellular and physiological effects resulting from hypoxia-dependent networks have been clearly shown to impact a number of human pathological states, including ischemic disease, diabetes, pulmonary

The zebrafish (Danio rerio) is a common vertebrate model organism in scientific research for studying vertebrate development, gene function, and regenerative abilities. Interestingly, this convenient

We all react to external factors, even the most cold-blooded person. We might hide our emotions, but there they are.

The same happens in cancer. Cells (both the tumour cells and the normal ones) react

Molecular biology experts have been telling us for a while that the Gateway® cloning vectors are easy-to-use, saving them significant time and effort.

Basically, the technology allows you to start with

As part of the innate immune response, Toll-like receptor 9 recognizes unmethylated CpG nucleotide sequences, which are very common in viruses and prokaryotes and more rare in vetebrates. Scientists

ISG15 ubiquitin-like modifier (ISG15) functions intracellularly as a Ubiquitin homologue and a cytokine. ISG15 induces production of IFN-gamma and augments NK/lymphokine-activated killer cell proliferation

Neurotrophins are important biomarkers in Neurobiology, including stem cell development to neural lineages. BDNF and NGF are the ones being studied in most cases. However, it has been found that neurotrophins

Whatever the research domain (oncology, cardiovascular diseases, Diabetis/obesity, inflammation, autoimmune disorders...), phosphorylation study is essential when looking for activation of cell signaling