Page 6 - Scientific Library
Tumour microenvironment and miRNA biomarkers
In previous posts, we have seen the role of inflammation and glycosylation in the tumour microenvironment (TME). All these are mainly factors at the protein level causing the tumour cells to evade the
Useful tip for better zebrafish whole-mount IHC staining
The zebrafish (Danio rerio) is a common vertebrate model organism in scientific research for studying vertebrate development, gene function, and regenerative abilities. Interestingly, this convenient
Tumour microenvironment and kinome studies
We all react to external factors, even the most cold-blooded person. We might hide our emotions, but there they are.
The same happens in cancer. Cells (both the tumour cells and the normal ones) react
Glycosylation studies in the inflammasome
In a previous post on tumour microenvironment (TME) and glycosylation, we indicated that new tools for studies on glycosylation of proteins were being developed. We are happy to announce that they are
ISG15 in Interferon-mediated signaling
ISG15 ubiquitin-like modifier (ISG15) functions intracellularly as a Ubiquitin homologue and a cytokine. ISG15 induces production of IFN-gamma and augments NK/lymphokine-activated killer cell proliferation
Physioxia or Hypoxia: what it's all about
Cell culture under oxygen controlled conditions: an improvement towards more predictive results
Oxygen concentration in tissues is a key factor for cell and organ survival. In normal conditions, partial
Direct access to Biomarker Profiling identification tools
Profiling tools have an increasing interest for identifying new biomarkers. Different tools are available, from classical gene profiling on DNA chips, RT-qPCR arrays, Protein arrays for secretome or
Don't miss any neurotrophin!
Neurotrophins are important biomarkers in Neurobiology, including stem cell development to neural lineages. BDNF and NGF are the ones being studied in most cases. However, it has been found that neurotrophins
7 popular phospho-specific antibodies
Whatever the research domain (oncology, cardiovascular diseases, Diabetis/obesity, inflammation, autoimmune disorders...), phosphorylation study is essential when looking for activation of cell signaling
Put the odds in your favour for your STED microsopy images
Stimulated emission depletion (STED) microscopy is an accurate process allowing super resolutive cell imaging. STED microscopy overcomes the limits of standard confocal laser scanning microscopes. In
Discovery of functional serum biomarkers
Lung cancer is one of the most common malignancies, and the leading cause of cancer-related fatality. Current diagnostic practices for common cancers rely heavily on imaging technologies. These