Page 8 - Scientific Library

In a previous post I discussed 3 new unique research tools for analyzing Amyloid peptide in Alzheimer’s Disease (AD). Today, I'd like to come back to the unique properties of the Amylo-Glo® fluorescent

Bioactive small molecules facilitate numerous types of Life Science research approaches (enzyme substrates, activators and inhibitors, cell signaling modulator, cell culture...). Accessing reasonably

Ubiquitin (Ub) is an 8 kDa  highly conserved polypeptide, commonly expressed in eukaryotic cells. Ub is added to lysine residues of the target proteins. This post-translational modification (known

Celastrol is a biologically active substance initially described in the traditional Chinese medicine. Celastrol (or (9ß,13α,14ß,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic

Deak AT et al. decipher the mechanisms by which mitochondria contribute to Ca2+ intracellular signaling. In their recent paper (1), they show that mitochondrial "Ca2+ buffering" close to the Endoplasmic

In Pharma screening departments there is a strong need for Ca²⁺ measurement methods.

Why is this?

GPCRs (G Protein Coupled Receptors) are still major targets of pharmaceutical screenings.

Around 30-40%

Following on from my previous post on biosimilars and biotherapeutics (or biologics), let's now take a look at some of the specific criteria for this kind of compound, which are not normally required

The U.S. Food and Drug Administration (FDA) has approved Velcade (Bortezomib) for the retreatment of adult patients with Multiple Myeloma who had previously responded to Velcade therapy and relapsed

DNA topoisomerase I and DNA topoisomerase II (Topo I and Topo II) are nuclear enzymes which regulate the topological state of the DNA helix by transiently breaking and rejoining DNA strands. They also

Current cancer vaccine strategies strive to efficiently deliver in situ