Page 4 - Scientific Library
PROTACs: A promising strategy in Drug Development
Thanks to its capability to recruit the natural protein degradation system of a cell, PROTACs (PROteolysis TArgeting Chimera) appears as a very promising
Multiplex Protein Assays: which one fits you best?
Multiplex protein assays allow multiple targets quantification in a single sample, a bit like performing up to 40 different ELISAs in one go. Outsourcing Multiplex Protein Quantification projects
Antibody Purification: Tips and Tricks
For all species, classes or size (FL vs. fragments)
Whatever the type of antibody production (hybridoma or recombinant protein production
Want to know more about your Biologics?
In new drug development pipelines, there is an increasing trend to switch from "small" to "large" molecules (also known as biologics). While the FDA guidance was quite specific with their recommendations
How can TR-FRET facilitate your cell signalling studies?
Time-Resolved Förster Resonance Energy Transfer (TR-FRET) is a robust and homogeneous fluorescence detection technology and a real alternative to ELISA to perform Cell Signalling studies.
World's first 3',3'-Cyclic CAMP ELISA
The cGAS-cGAMP-STING cell signalling pathway plays a critical role in antiviral and antitumor immunity as well as mediating autoimmune responses. Dysregulation or aberrant activation of
How to monitor inflammatory cytokines in anti-COVID drug discovery
The close relation between Severe Acute Respiratory Syndrome (SARS), unpaired adaptive immune responses and overexpression of inflammatory cytokines has been described more than a decade
How are mRNA vaccines changing drug discovery?
mRNA vaccines are developing very quickly with dozens of ongoing clinical trials against cancers or infectious diseases (e.g. HIV or more recently SARS-Cov-2). Recombinant monoclonal antibody (mAB) based
Immuno-Oncology: 6 must-haves to boost your projects
Alone, or in combination with other therapies, Immuno-Oncology (I-O) appears currently as one of the most promising research fields to fight cancer. Nevertheless, developing breakthrough
How can you get your mRNA ready in only a few weeks?
Synthetic mRNA is indeed the highway for today's therapeutics, whether you're working on developing new drugs against cancer targets, or whether you aim to develop new vaccines, Covid-19 being one of them.
Protocole de Western Blot (WB) - Recommandé par les utilisateurs d'anticorps Tebubio
Protocole de Western Blot (WB) - Recommandé par les utilisateurs d'anticorps Tebubio
Protocole WB & conseils techniques - améliorez la reproductibilité de vos résultats
Tips and tricks to design and test qPCR primers - advanced procedure
Tips and tricks to design and test qPCR primers - advanced procedure
Design and test your own qPCR primers
- Find the NCBI Gene page for the gene you would like to