Page 9 - Scientific Library
High resolution structure of the TRPA1 channel protein
One of the hottest news last month was the high resolution structure of the TRPA1 ion channel protein.
Thiostrepton: a novel lead compound against Dengue?
Dengue Virus (DenV) is transmitted by mosquito vectors. It infects 50-100 million people each year and is at the origin of Dengue Fever and the more lethal Dengue Hemorrhagic Fever (DHF) and Shock Syndrome
20S Proteasome inhibitors and Leptin against obesity
The World Health Organization (WHO) estimated in 2008 that 1.4 billion adults worldwide were overweight and of these 500 million were obese with risks for developing type 2 diabetes, hypertension and cardio-vascular
Pharmacological agents which alleviate Pain
Chronic pain of varying types including inflammatory pain, cancer pain and neuropathic pain is an increasing health problem for which there are inadequate therapeutic options.
Many new targets for analgesic
Cancer stem cells - friend or foe in the fight against cancer?
Today, following our series on Tumour Microenvironment (TME), and leading on from three recent publications, let's discuss Cancer Stem Cells (CSCs).
CSCs are part of the TME, as they reside in
Basics about insulin and dedicated research tools
Diabetes is a major health concern. And its research can be a nightmare sometimes. tebu-bio strive to offer a comprehensive range of research tools and services to study Obesity, Diabetes, and Metabolic
O-Glucuronide synthesis made easy
Efficient screening of PPAR active compounds
Peroxisome Proliferator-Activated Receptors (PPARs) are ligand-activated transcription factors of the Nuclear Receptor superfamily. PPAR active compounds are of significant interest in multiple pharmaceutical
6 popular Microtubule agents used in in vitro tubulin assays
Microtubules are key components of the cytoskeletal structure of eukaryotic cells. Composed of alpha- and beta- tubulin sub-units, microtubules are dynamic entities
How to easily obtain a highly purified untagged recombinant protein
Isolation of highly purified untagged proteins is crucial in today's R&D programs. Up to now, recombinant protein production approaches were often based on the use of "tags" to make protein purification
How to modulate ion channels
Ion channels play an important role in perception and transmission of pain sensations. Furthermore, dysfunctions of certain ion channels are involved in neuronal disorders, such as epilepsy, Alzheimer's