Page 7 - Scientific Library
Mutant or wild-type: 7 effective means to screen and profile Human EZH2 Methyltransferase
Histone-lysine N-methyltransferase EZH2  is a methyltransferase involved in transcriptional gene regulation. Together with with EED, RbAP48, SUZ12 and AEBP2, EZH2 forms a 5-member complex that adds
Main factors for different cell types...
In my previous post, we focused on 6 cytokine growth factors for cell culture. This time, we will try to find the best factor for each main cell type.
- Established Cell Lines: Â this established cell culture
Focus on the JAK-STAT pathway...
The Janus kinase (JAK) / Signal Transducer and Activator of Transcription (STAT) pathway a key regulator of cellular proliferation, differentiation, migration, apoptosis and survival. Numerous cytokines,
Specific cytokines & growth factors in... angiogenesis, endothelial cells
Angiogenesis is the growth process of new blood vessels from pre-existing one's. It's a normal physiological process, observed during embryonic development. But it's also a pathological process, essentially
Obesity, Diabetes, Metabolic syndrome new research tools
Insulin and Glucagon are involved in glucose homeostasis in addition to other factors secreted by the adipose tissue (adipokines). Insulin and Glucagon are produced by the endocrine pancreas. While
Specific cytokines & growth factors in... inflammation
Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Numerous cytokines are present within inflammatory
Primary cell sourcing: Cryopreserved Human Adult Sebocytes
Sebocytes are emerging cellular models to study skin biology but also to design new compounds to regulate acne, seborrhoea and other sebaceous gland-related diseases. Easy access to cryopreserved and
Modulate hepatic inflammation
Kupffer cells are macrophages endogenous to the liver which have the ability to modulate hepatic inflammation and injury associated with various pathophysiologies and toxicities. Pro-inflammatory cytokines
Human Primary Sebocyte assay for compound testing on lipid metabolism
Sebocytes belong to the epidermal ecosystem together with hair follicules or in sebaceous glands. Sebocytes play a key role in skin health by producing sebum. These cells are now at the center of researchers'
Specific cytokines & growth factors in... neurobiology!
Neurobiology is the study of cells of the nervous system and their organization into functional circuits that process information and mediate behavior.
Neurotrophic factors
Neurotrophic factors are
Specific cytokines & growth factors in... hematology!
Hematology is the study of blood, blood-forming organs and blood diseases. The formation of blood cells is referred to as hematopoiesis. All cellular components of the blood are derived from hematopoietic
Specific cytokines & growth factors in... apoptosis!
Apoptosis is the process of programmed cell death. Upon induction of apoptotic processes, cell undergo characteristic morphological changes (blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation,