Page 6 - Scientific Library

Cell culture under oxygen controlled conditions: an improvement towards more predictive results

Oxygen concentration in tissues is a key factor for cell and organ survival. In normal conditions, partial

Profiling tools have an increasing interest for identifying new biomarkers. Different tools are available, from classical gene profiling on DNA chips, RT-qPCR arrays, Protein arrays for secretome or

Assessing gene transcription as an endpoint for determining induction of drug metabolizing enzymes and transporters has become the “method of choice” in the FDA’s latest draft Guidance for Industry drug

Following our series of posts on the role of exosomes in cancer (TME, signaling), let's have a look at Neurobiology today. Because exosomes are everywhere (even in beer!).

Use of human samples including peripheral blood mononuclear cells (PBMCs) in drug discovery is critical for increasing the chances of success for a small molecule screen hit. A review based on recent

Lung cancer is one of the most common malignancies, and the leading cause of cancer-related fatality. Current diagnostic practices for common cancers rely heavily on imaging technologies. These

The urogenital system is the organ system of the reproductive organs and the urinary system. These are grouped together because of their proximity to each other, their common embryological origin and the

In this post, I'd like to  introduce human aortic, brachiocephalic, carotid artery and coronary artery cells isolated by Cell Applications Inc. In a future post, I'll be highlighting human internal

The PI3K/Akt/mTOR pathway is an intracellular signaling pathway important in regulating the cell cycle. It is directly related to cellular quiescence, proliferation, cancer, and

In a previous post, I introduced several models to study the cardiac human system. This first post introduced human aortic, brachiocephalic, carotid artery and coronary artery cells isolated by Cell Applications

The IL-1 family has long been known as a key player in the effector role of macrophages in innate defence against tumours and infections. It plays an important role in the field of natural / innate immunity

Leukocytes adhere to blood vessels as a mechanism to enter tissue where there is inflammation. Inadvertently, they pile up sickle cell red blood cells.

Mutations in the hemoglobin gene can render a person