Luciferase is the general term given to a class of oxidative enzymes that catalyze reactions that give off light, a process known as bio-luminescence (Fig. 1). In biology,
Scientific Library
How to monitor mitophagy in mammalian cells
Mitochondria keep cells "healthy" in their environment. In this post, we'll take a look at a new fluorescent assay for the monitoring of mitophagy, a process aimed at clearing damaged or superfluous mitochondria
3 new mitochondrial research reagents
Research tools aimed at exploring mitochondria are becoming more and more popular and cover multiple experimental applications. They go from primary antibodies validated for immuno-assays (seeÂ
LipiDye fluorescent probe for lipid droplet monitoring in live cells
LipiDye lipid droplet Green* is a new highly sensitive fluorescent probe for detecting lipid droplets in live or fixed cells. In this, let's review the characteristics of this dye which is compatible
Fluorescence microscopy: how to improve your Live Cell Imaging
For more than 2 years now, the Silicon Rhodamine-like (SiR) technology has allowed the live cell imaging field with fluorescence microscopy to evolve significantly.
Fluorescent SiR-probes have appeared
MitoTools: Mitochondrial research has never been so easy
Involved in many physiological processes (apoptosis, aging, cell signalling..) and numerous diseases (cardiovascular disorders, to cancer and neuro-degenerative diseases…), Mitochondria have become more
3 colour Live Cell Imaging - Actin, Tubulin and DNA
Following on from the popular SiR-Probes, earlier this year Spirochrome introduced new SPY probes, as presented in this post.
Take a few minues to watch this video of the SPYâ„¢ Actin, Tubulin and DNA
What mitochondria related diseases?
All human and living beings have mitochondria. These are tiny cellular organisms present in nearly every cell of an individual. They are located more precisely inside the cells, in their nucleus. The main
Why replace fluorescent markers with lanthanide nanoparticles to improve detection?
According to the WHO (World Health Organization), early diagnosis of diseases is one of the key factors in the world to save lives and reduce the cost of treatment. Faced with these recommendations, in
Understanding cellular senescence and oxygen consumption rate
Understanding cellular senescence and oxygen consumption rate
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A recent paper published in Science reported a 50% reduction in mortality and improved immune response in old mice infected with SARS-CoV-2
Relationship between antitumor effects and active oxygen
Relationship between antitumor effects and active oxygen
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ROS (Reactive oxygen species) are highly reactive oxygen species mainly generated during the ATP synthesis process in mitochondria. While it is
Unveiling the Next Generation of Actin Imaging
Advancing Live-Cell Actin Imaging with Spirochrome New Products
Actin cytoskeleton imaging is a cornerstone of cellular biology, playing a pivotal role in understanding cell motility, morphology, and