Luciferase is the general term given to a class of oxidative enzymes that catalyze reactions that give off light, a process known as bio-luminescence (Fig. 1). In biology,
Scientific Library
Article
How is Amylo-Glo a brighter, longer lasting and higher definition Amyloid plaque marker?
April 18, 2014
In a previous post I discussed 3 new unique research tools for analyzing Amyloid peptide in Alzheimer’s Disease (AD). Today, I'd like to come back to the unique properties of the Amylo-Glo® fluorescent
Article
Modulating or inhibiting Caspase activities
May 27, 2015
In a previous post, I discussed Caspases as pharmaceutical targets - how to screen for inhibitors?
Today I would like to concentrate on Caspase inhibitors/modulators, which allow for in-depth characterisation
Article
Which Histone (De)Methyltransferase modulators to choose?
November 11, 2015
Histone Methyltransferases (ex. EZH1 and EZH2, and G9a) and their counter-parts (Histone demethylases like JARID1, the KDM4, and the JMJD family) have become promising targets for inhibitor screenings,
Article
Rolipram slows tau accumulation and AD
January 28, 2016
Simultaneous localization of Amylo-Glo® positive amyloid plaques (blue), GFAP positive hypertrophied astrocytes (green) and activated microglia (red) in the hippocampus of the AD/Tg mouse. Combined UV,