Page 5 - Scientific Library

Chronic pain of varying types including inflammatory pain, cancer pain and neuropathic pain is an increasing health problem for which there are inadequate therapeutic options.
Many new targets for

A few months ago I read a very nice blog post from our friends at TriLink Biotechnologies giving the chemist's perspective on the excitement surrounding "Click

Microtubules are key components of the cytoskeletal structure of eukaryotic cells.

Ion channels play an important role in perception and transmission of pain sensations. Furthermore, dysfunctions of certain ion channels are involved in neuronal disorders, such as epilepsy, Alzheimer's

G Protein Coupled Receptors (GPCR) and ion channels are important targets in drug development. Both target classes represent membrane proteins which require convenient and robust cell-based assays for

For one year now,  SiR-Actin and SiR-Tubulin, the second generation of tools to stain actin and tubulin in

In their most recent publication

Statins are HMG-CoA reductase inhibitors, well-known  medications for treating Hypercholesterolemia. Simvastatin is a member of this "Statin family" and controls

Thousands of researchers spend time pampering their primary cells and cell lines every day, with the aim of defining their optimal cell culture conditions. Researchers are in effect trying to control numerous

Histone Methyltransferases (ex. EZH1 and EZH2, and G9a) and their counter-parts (Histone demethylases like JARID1, the KDM4, and the JMJD family) have become promising targets for inhibitor screenings,

Visualizing fixed cells and tissues only gives snap shots of cellular processes. Over the past years, more and more cellular