Page 5 - Scientific Library
5 Cytoskeletal Modeling Molecules
Cytoskeleton modeling molecules are relevant when trying to improve one's understanding of cytoskeletal molecular modeling and associated mechanisms. Together with actin binding proteins, tubulin-based
15 Ubiquitin - Proteasome inhibitors for cancer research
With more than 100 types of cancers affecting any part of the body, cancer is one of the leading causes of death in the world. It has an enormous impact on well-being, both for those with the diagnosis
The TRPV1 Pain Receptor activates T cells
The Transient Receptor Potential (TRP) ion channel family participates in numerous functions of the Nervous System. A recent publication tends to indicate that TRP might also be of interest for therapeutical
Cell counting made easy!
After you've read this post, I hope that you'll agree that what the title of the post announces is the right assumption. How? Read on!
I invite you to take a look at Cyto-X, which is a ready-for-use
Antibiotics and microbial metabolites - revisited
What are metabolites?
Microorganisms live in a world of chemical signals. They use small molecular weight compounds, known as metabolites, to regulate their own growth and development, to encourage other
PGE2 role in carcinoma chemoresistance via CSC repopulation
The involvement of Prostaglandin E2 (PGE2) in cancer development has already been described (see the post "Tumour microenvironment – the dark side of PGE2). Recently, Kurtova et al. confirmed this
HD-LCI video of HUVEC Transfection with Cytofect Kit
See human cells glow with green fluorescent protein in this time-lapse video. These images were captured over 20 hours via Lumascope 620.
[youtube https://www.youtube.com/watch?v=k5esUe_rrr4]
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High Definition
Hepatic Cellular Models
A wide range of in vitro models are used in preclinical drug testing for the investigation of ADME-Tox (Absorption, Distribution, Metabolism, Excretion and oxicity) properties of New Chemical Entities
How to manipulate and measure Autophagy?
The term Autophagy was introduced by Christian de Duve during the Ciba Foundation Symposium on Lysosomes - which was held in London in February 1963. In 1974 he was honoured with the Nobel price in
Differentiate between Apoptosis, Necroptosis, Autophagy & Ferroptosis
Cell death can be caused by external factors such as infection or trauma - a process which is call necrosis. On the other hand, cell death can be mediated by intracellular programs - in this cases we talk
Modulating or inhibiting Caspase activities
In a previous post, I discussed Caspases as pharmaceutical targets - how to screen for inhibitors?
Today I would like to concentrate on Caspase inhibitors/modulators, which allow for in-depth characterisation