Page 13 - Scientific Library

DNA methylation and histone post-translational modifications are key epigenetic factors.

They regulate gene expression by interfering with the chromatin structure and the binding of effector proteins

The authors have investigated the role Toll-Like Receptor 9 (TLR9) in host defense during Pseudomonas aeruginosa lung infection.

This team showed the inhibitory effects of TLR9 on innate immune response

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression and influence numerous cellular functions. Together with mature RNAs and small molecules, mature miRNAs can induce forced reprogramming