2',3'-cGAMP - 200 ug

Activity: Endogenous STING agonist . Function/Pharmacology: 2',3'-cGAMP (CAS 1441190-66-4) is an endogenous STING (stimulator of interferon genes) agonist.1 Produced from ATP and GTP via the action of cGMP-AMP synthase (cGAS) which acts as a cytosolic DNA sensor.2,3 Induces autophagy which is a mechanism for clearance of DNA and viruses in the cytosol.4 DNA damage stimulates 2’,3’-cGAMP which stimulates an inflammatory response.5 Chemical Name: Adenylyl-(3’5’)-2’guanylic acid, cyclic nucleotide, disodium salt

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 10-1639

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Storage Temperature

 -20°C

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 Focus Biomolecules

CAS Number

 1441190-66-4
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CAS Number: 1441190-66-4