Z-Arg-Arg-MbNA (Cathepsin B Substrate) - 25 mg

CAS Number: 100900-19-4Molecular Weight: 619.32Salt Form: TFAPurity: >96%Sequence (3-letter): Z-Arg-Arg-4MbNASequence (1-letter): Z-RR-4MbNAStorage: -20 °C or belowZ-Arg-Arg-MbNA is a fluorogenic substrate for Cathepsin B. Cathepsin B is a lysosomal cysteine protease with a role in intracellular protein degradation. Cathepsin B crosses the blood-brain barrier and elevated levels are implicated in many neurological maladies including traumatic brain injury epilepsy and Alzheimer's disease.Activity is quantified by release of free fluorescent 4-Methoxy-β-naphthylamine (4MβNA) which excites at 335-350 nm and emits at 410-440 nm.