WY-14643 - 250 mg

Activity: PPARα agonist . Function/Pharmacology: Selective PPARα agonist (EC50=0.63, 32 and >100 µM for PPARα,γ and δ, respectively).1 Displays anti-inflammatory activity2 and reduces LPS-induced inflammation in alveolar epithelial cells3. Induces “browning” of white adipocytes in combined treatment with retinoic acid.4 Stimulates ADAM10-mediated proteolysis of amyloid precursor protein in a mouse model.5 Down regulates NFκB transcriptional activity. Review.6 Chemical Name: 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid

Supplier Catalog Number

 10-1137

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Storage Temperature

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Supplier name

 Focus Biomolecules

CAS Number

 50892-23-4
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€259.00
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CAS Number: 50892-23-4