Sphingosine 1-Phosphate Antibody - 50 ug

Purified Anti-Sphingosine 1-Phosphate (S1P) monoclonal antibody.Subclass: IgGk1Source: MouseApplications: ELISA Immunohistochemistry ImmunocytochemistrySphingosine 1-Phosphate (S1P) is a key component of the sphingolipid signaling cascade. S1P initiates a proliferative pro-angiogenic and anti-apoptotic sequence of events contributing to cancer progression. Recently scientific literature has suggested that S1P is a potent tumorigenic growth factor that is likely released from tumor cells and that S1P may be a novel biomarker for early stage cancer detection. Sphingosine kinase has also been shown to be up-regulated in a variety of cancer types. S1P antibody (LT1002) was originally developed and patented at Lpath Therapeutics. Powered by Bioz See more details on BiozSelected Publications1) Visentin B Reynolds G Sabbadini R. (2012) Immunohistochemical detection of sphingosine-1-phosphate and sphingosine kinase-1 in human tissue samples. Methods Mol Biol. 874:55-67.2) O'Brien N Jone