Mouse anti-CD8b, clone EBS-CD-007 (Monoclonal) - 100 ug

EBS-CD-007 recognized a protein of 32 kDa, identified as CD8b. The CD8 molecule consists of α and β chains, which are disulphide-linked into heterodimers or homodimers. CD8 is expressed on a T-cell subset (cytotoxic-suppressor T-cells), thymocytes and NK cells. The majority of CD8+ T-cells express CD8 as heterodimer. Some subpopulation of CD8+ T-cells as well as NKcells may express homodimer. CD8 functions as a co-receptor is concert with TCR for binding the MHC class I/peptide complex. HIV-2 envelope glycoprotein binds CD8 α chain but not β chain.